Project manager: Gary Chinga Carrasco

New functionalized medical devices for surgical interventions in the pelvic cavity

The incidence of cancer of all kinds is growing all over the world, and thereby the number of surgical interventions in the field of oncological surgery records a continuous growth year after year. In some cases, the complete removal of one or more organic structures from the pelvis is required. These surgical interventions are associated with a high post-operative morbidity and mortality. The pelvic prosthesis developed in MedIn project will be designed to increase the quality of life of people after surgical interventions. Other complications which may occur refer to overall infectious. In general, wound infection associated with this type of surgical interventions is reported to be as high as 40%. This remains an unmet need to be covered through an innovative wound dressing that will be developed within the scope of this project.

This project is supported by a grant of the Romanian National Authority for Scientific Research and Innovation, CCCDI – UEFISCDI, project number COFUND-MANUNET III-MedIn-1, within PNCDI III, contract no. 33/2018, and by the Research Council of Norway, Grant: 283895, through the MedIn project, MNET17/NMCS-1204 – “New functionalized medical devices for surgical interventions in the pelvic cavity”.

Partners;

  • RISE PFI (Coordinator)
  • Oxy Solutions AS
  • The National Institute for Research & Development in Chemistry and Petrochemistry, Bucharest
  • LTHD corporation
  • Carol Davila University of Medicine and Pharmacy, Bucharest
Photos: Upper photo from the Kick off meeting at ICECHIM. Lower photos: Project meeting at RISE PFI.

Project period: 2018-2019

Meetings

190930 – Project meeting, Oxy Solutions, Oslo, Norway

190220 – Project meeting, LTHD corp. Timisoara, Romania.

180921 – Project meeting, RISE PFI, Trondheim, Norway

180125 – Kick-off Meeting, Bucharesti, Romania

Dissemination

Published articles

Chiulan I, Panaitescu DM, Radua, E-R, Frone AN, Gabor RA, Nicolae CA, Jinescu G, Tofan V, Chinga-Carrasco G. Comprehensive characterization of silica-modified silicon rubbers. J. Mechanical Behavior Biomedical Materials. September 2019, 103427.

Eduardo Espinosa, Daniel Filgueira, Alejandro Rodríguez and Gary Chinga-Carrasco. Nanocellulose-Based Inks—Effect of Alginate Content on the Water Absorption of 3D Printed Constructs. Bioengineering 2019, 6(3), 65; https://doi.org/10.3390/bioengineering6030065

Henriette R. Nordli, Brita Pukstad, Gary Chinga-Carrasco, and Anne M. Rokstad. Ultrapure Wood Nanocellulose—Assessments of Coagulation and Initial Inflammation Potential. ACS Applied Bio Materials.

Gary Chinga-Carrasco. Novel Biocomposite Engineering and Bio-Applications. Bioengineering 2018, 5(4), 80; https://doi.org/10.3390/bioengineering504008. Editorial Special Issue.

Conferences

Ioana Chiulan, Denis M. Panaitescu, Adriana Nicoleta Frone, Cristian Andi Nicolae, Raluca A. Gabor, Sorin Valentin Rădiţoiu, Elvira Alexandrescu, Bogdan Trică. Cellulose/ethylene glycol methyl ether acrylate 3D structure with controllable physical properties. 11th International conference on Advanced Nanomaterials, 2018. Aveiro, Portugal. Poster.

Ioana Chiulan, Denis Panaitescu, Adriana Frone, Cristian Nicolae, Raluca Gabor, Elena Radu, Claudia Minciuleanu, Elvira Alexandrescu. Composite hydrogels based on bacterial cellulose and oligo(ethylene glycol) acrylates as drug delivery systems. 7th EuCheMS Chemistry Congress, 2018. Liverpool, UK. Poster.

Ioana Chiulan, Elena Ruxandra Radu, Raluca Augusta Gabor, Cristian Andi Nicolae, Denis Mihaela Panaitescu, Adriana Nicoleta Frone, Valentin Rădiţoium. Silane functionalized fumed silica for silicones rubber composites. The XXXV-th Romanian Chemistry Conference, 2018. Caciulata, Romania. Oral presentation.

Gary Chinga-Carrasco, Henriette Rogstad Nordli, Anne Mari Rokstad, Brita Pukstad, Ultrapure nanocellulose – Cytocompatibility and 3D printing of wound dressings. Nanocellulose research seminar, Trondheim, Norway (2018), Poster.

Gary Chinga-Carrasco, 3D printing of bio-based medical devices. 3D printing of biomaterials. 2nd seminar hosted by VTT and FPInnovations, Helsinki, May 29, 2018. Finland. Invited talk.

Gary Chinga-Carrasco, 3D printing – soft and solid biobased constructs for biomedical applications, 15th International Symposium on Bioplastics, Biocomposites and Biorefining (ISBBB 2018). Guelph, Canada. Invited talk.

Nicolae Calin Brandabur , How Far Has 3D Printing Come to Industry. Uppsala, November 3rd, 2018. Sweden.

Electronic media

191218 – The MedIn project has made great progress!